Inertia is powerful and the response time is very quick. Just be sure your server is providing the proper data quickly. I try to keep all response times under 200ms.
I'm currently working on a desktop app and the performance is literally like a local desktop app. That may not hold up at full scale, but it's a good place to start.
Inertia becomes even more interesting when stepping slightly outside the standard REST approach. So, for example, sometimes I put the index and edit form on the same page. And Vue's ability to conditionally show, hide or style components also provides very fast and powerful UI features.
But if you're just doing a basic REST style app with a few resources, then Inertia could be overkill for that purpose.
I've also spent some time using Filament, which is really great! But, for now, my go-to development stack is still Inertia with Vue and Tailwind. Looking forward to Inertia 2.0!