I switched from using Bootstrap to Tailwind (in new projects) nearly a year ago. It was a little overwhelming at first because I had to figure out how to create the components from scratch (as Tailwind only provides the granular building blocks), but looking at and copying from open-source component libraries such as Flowbite and PenguinUI helped.
Flowbite (and related component libraries) also comes with the bonus of built-in JavaScript functionality for things such as modals and tooltips, something that Tailwind doesn't include.
Tailwind does require some basic CSS knowledge as that's all it's doing, letting you control your styling from the HTML. I was no CSS expert before, and neither am I now. But practice makes perfect, and there's a variety of resources out there. AI (ChatGPT for me) can also help in scaffolding basic page designs.
I found it helpful to recreate Bootstrap's container and breakpoints to make things easier and more familiar, especially if migrating a current application. This guide and example should give you a basic starting point.
Of course, if you like Bootstrap and it works for your current workflow, I don't see a big reason to change completely. I switched over as I enjoyed better control over the design and layout with Tailwind, whereas Bootstrap is a little harder to override and customize depending on how you do it.
