It's subjective but I prefer not using livewire, I suggest a React or Vue approach. But Axios JS is many times used behind the scenes anyway.
Some custom frond end work with regular javascript and Axios JS is real easy to achieve.
I tend to like stable, not the latest hot thing that's only been around a few months.
Also with React or Vue I think you have more custom control when needed.
But just my 2 cents.